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  • A European Union flag, with a hole cut in the...

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    A European Union flag, with a hole cut in the middle, flies at half mast outside a home in Knutsford, Cheshire after today's historic referendum on June 24, 2016 in Knutsford, United Kingdom.

  • A dog waits as its owner casts their ballot paper...

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    A dog waits as its owner casts their ballot paper in a polling station set up in the grounds of a private residence near Fleet, southwest of London, on June 23, 2016.

  • A woman rides a bicycle as she leaves a polling...

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    A woman rides a bicycle as she leaves a polling station at the Royal Hospital in Chelsea, west London on June 23, 2016.

  • Supporters of the Stronger In campaign react after hearing results...

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    Supporters of the Stronger In campaign react after hearing results in the EU referendum at London's Royal Festival Hall Friday, June 24, 2016. On Thursday, Britain voted in a national referendum on whether to stay inside the EU.

  • Chancellor George Osborne speaks at The Treasury, where he moved...

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    Chancellor George Osborne speaks at The Treasury, where he moved to try to calm market turmoil triggered by the pro-Brexit vote on June 27, 2016, in London.

  • A "Remain" campaign office in Gibraltar on June 23, 2016.

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    A "Remain" campaign office in Gibraltar on June 23, 2016.

  • A teller counts ballot papers at the Titanic Exhibition Centre...

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    A teller counts ballot papers at the Titanic Exhibition Centre in Belfast, Northern Ireland, after polls closed in the EU referendum Thursday, June 23, 2016. Britain's referendum on whether to leave the European Union was too close to call early Friday, with increasingly mixed signals challenging earlier indications that "remain" had won a narrow victory.

  • A customer looks along a line outside a foreign currency...

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    A customer looks along a line outside a foreign currency exchange bureau in London on June 22, 2016. Some Britons were seeking to buy euros and dollars ahead of the "Brexit" vote, fearing their currency would be devalued if Britain opted to leave the EU.

  • A polling clerk secures a polling station sign to a...

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    A polling clerk secures a polling station sign to a fence standing outside the Greenwich Heritage Centre, set up as a polling station, in London on June 23, 2016.

  • A member of the Blues and Royals, one of the...

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    A member of the Blues and Royals, one of the squadrons that form the Household Cavalry Mounted Regiment, sits upon his horse while standing guard on Whitehall in central London on June 28, 2016.

  • UK Independence Party (UKIP) leader Nigel Farage and "Leave" campaign...

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    UK Independence Party (UKIP) leader Nigel Farage and "Leave" campaign proponent poses for photographers as he leaves a polling station south of London on June 23, 2016,

  • An illuminated "Vote Today" sign is pictured atop of the...

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    An illuminated "Vote Today" sign is pictured atop of the BT Tower in central London on June 23, 2016.

  • People walk over Westminster Bridge wrapped in Union flags toward...

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    People walk over Westminster Bridge wrapped in Union flags toward the Queen Elizabeth Tower and The Houses of Parliament in central London on June 26, 2016.

  • In this image from TV, Andrea Leadsom, one of two...

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    In this image from TV, Andrea Leadsom, one of two candidates to become leader of the Conservative Party, reads a statement to announce her withdrawal from the race in London on July 11, 2016. Leadsom says she has concluded she does not have "sufficient support" to win, and will leave Theresa May as the sole candidate to become Britain's prime minister.

  • Union flags fly as banners across a street in central...

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    Union flags fly as banners across a street in central London on June 28, 2016.

  • Residents cast their votes on the EU referendum at a...

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    Residents cast their votes on the EU referendum at a polling staton at the East Hull Boxing Club in Kingston-Upon-Hull, northern England on June 23, 2016.

  • Nigel Farage, the leader of the UK Independence Party, celebrates...

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    Nigel Farage, the leader of the UK Independence Party, celebrates and poses for photographers as he leaves a "Leave.EU" organization party for the British European Union membership referendum in London, Friday, June 24, 2016. On Thursday, Britain voted in a national referendum on whether to stay inside the EU.

  • British Prime Minister David Cameron, a "Remain" proponent, and his...

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    British Prime Minister David Cameron, a "Remain" proponent, and his wife Samantha greet photographers after casting their votes in the EU referendum at a polling station in London, on June 23, 2016.

  • Residents walk into a polling station to cast their vote...

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    Residents walk into a polling station to cast their vote in north London on June 23, 2016.

  • A man leaves a polling station set up inside a...

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    A man leaves a polling station set up inside a hairdresser's salon in Kinston upon Hull in northern England on June 23, 2016.

  • British Conservative party leadership candidate Theresa May speaks to members...

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    British Conservative party leadership candidate Theresa May speaks to members of the media at The St. Stephen's entrance to the Palace of Westminster in London on July 7, 2016.

  • Chelsea pensioners arrive at a polling station near to the...

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    Chelsea pensioners arrive at a polling station near to the Royal Chelsea Hospital, London, to vote in Britain's EU referendum on June 23, 2016.

  • People walk past a "Vote Leave" sign as they arrive...

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    People walk past a "Vote Leave" sign as they arrive to cast their ballots at a polling station in Belfast, Northern Ireland, on June 23, 2016.

  • People arrive to cast their ballots at a polling station...

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    People arrive to cast their ballots at a polling station set up in a village hall in Penshurst, south-east of London on June 23, 2016.

  • Chelsea pensioners are ushered into a polling station to cast...

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    Chelsea pensioners are ushered into a polling station to cast their ballot papers at the Royal Hospital in Chelsea, west London on June 23, 2016.

  • A woman poses looking at a chart showing the drop...

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    A woman poses looking at a chart showing the drop in the pound (Sterling) against the U.S. Dollar in London on June 24, 2016 after Britain voted to leave the EU.

  • A statue of Winston Churchill is silhouetted against the Houses...

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    A statue of Winston Churchill is silhouetted against the Houses of Parliament and the early morning sky in London, Friday, June 24, 2016. Britain entered uncharted waters Friday after the country voted to leave the European Union, according to a projection by all main U.K. broadcasters.

  • People walk down the Mall in central London on June...

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    People walk down the Mall in central London on June 26, 2016.

  • A man walks past a polling station sign outide the...

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    A man walks past a polling station sign outide the Royal Hospital in Chelsea, west London, on June 23, 2016.

  • A woman leaves a polling station being used in the...

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    A woman leaves a polling station being used in the EU referendum at Batley Town Hall in west Yorkshire, England, in the constituency of murdered Labour MP Jo Cox on June 23, 2016.

  • A campaigner for the "Stronger In" campaign, the official "Remain"...

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    A campaigner for the "Stronger In" campaign, the official "Remain" campaign, canvasses for supporters in London on June 23, 2016.

  • A man wearing a "Vote Remain" t-shirt walks in the...

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    A man wearing a "Vote Remain" t-shirt walks in the rain in central London on June 23, 2016.

  • Chelsea pensioners vote at the Royal Hospital during the EU...

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    Chelsea pensioners vote at the Royal Hospital during the EU Referendum polling day in London on June 23, 2016.

  • The flags of the United Kingdom and Europe fly June 24,...

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    The flags of the United Kingdom and Europe fly June 24, 2016, in Brussels.

  • A woman casts her vote in a bus being used as...

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    A woman casts her vote in a bus being used as a temporary polling station in Kingston-Upon-Hull, northern England, on June 23, 2016.

  • Copies of German magazine Der Spiegel featuring the headline "Please...

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    Copies of German magazine Der Spiegel featuring the headline "Please don't go!" sit on a rack inside a newsagents store in Berlin on June 18, 2016.

  • Olivia Sudjic holds up a placard in favor of the...

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    Olivia Sudjic holds up a placard in favor of the remain camp by a polling station in north London on June 23, 2016.

  • An American tourist stands near the Houses of Parliament in...

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    An American tourist stands near the Houses of Parliament in London the day after the majority of the British public voted to leave the European Union.

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PUBLISHED: | UPDATED:

Britain voted to leave the European Union after a bitterly divisive referendum campaign, toppling the prime minister Friday, sending global markets plunging and shattering the stability of a project in continental unity designed half a century ago to prevent World War III.

The decision launches a yearslong process to renegotiate trade, business and political links between the United Kingdom and what would become a 27-nation bloc, an unprecedented divorce that could take a decade or more to complete.

“The dawn is breaking on an independent United Kingdom,” said Nigel Farage, leader of the U.K. Independence Party. “Let June 23 go down in our history as our independence day!”

Prime Minister David Cameron, who had led the campaign to keep Britain in the EU, said he would resign by October and left it to his successor to decide when to invoke Article 50, which triggers a departure from the European Union.

“I will do everything I can as prime minister to steady the ship over the coming weeks and months,” he said, “but I do not think it would be right for me to try to be the captain that steers the country to its next destination.”

Polls ahead of the vote had shown a close race, and the momentum had increasingly appeared to be on the “remain” side over the last week. But in an election Thursday marked by notably high turnout — 72 percent of the more than 46 million registered voters — “leave” won with 52 percent of the votes.

The result shocked investors, and stock markets plummeted around the world, with key indexes dropping 10 percent in Germany and about 8 percent in Japan and Britain.

The Dow Jones industrial average dropped 611 points, or 3.4 percent, its biggest fall since August.

The euro fell against the dollar and the pound dropped to its lowest level since 1985, plunging more than 10 percent from about $1.50 to $1.35 before a slight recovery, on concerns that severing ties with the single market will hurt the U.K. economy and undermine London’s position as a global financial center. Bank of England Gov. Mark Carney sought to reassure markets and promised to take “all the necessary steps to prepare for today’s events.”

Also seeking to calm frayed nerves was the most prominent “leave” campaigner, Boris Johnson. Taking a somber tone unusual for the flamboyant former London mayor, he described the EU as a noble idea which was no longer right for Britain. He said the result in no way means the United Kingdom will be “less united” or “less European.”

Even as he spoke, however, Scotland’s First Minister Nicola Sturgeon said a second Scottish referendum on independence from the United Kingdom is now “highly likely.” Scotland voted in 2014 to remain a part of the U.K. but that decision was seen by many as being conditional on the U.K. remaining in the EU.

But nothing matched the shock of the people in the capital, London, where some 10 percent of the population is from the EU. Christine Ullmann, a German who worked on the campaign urging other Europeans to “Hug a Brit,” exemplified the sadness and sense of loss.

“What about Brits who believe in the goodness of their society who find themselves in a society where they can’t travel and work freely in Europe?” she said. “I feel really sad for them. They’ve lost more.”

London Mayor Sadiq Khan felt it necessary to reach out to the 1 million Europeans in the capital to underscore they were still “very welcome here.”

“We all have a responsibility to now seek to heal the divisions that have emerged throughout this campaign — and to focus on what unites us, rather than that which divides us,” he said.

Britain would be the first major country to leave the EU, which was born from the ashes of World War II as European leaders sought to build links and avert future hostility. With no precedent, the impact on the single market of 500 million people — the world’s largest economy — is unclear.

Leaders from across the EU voiced regret at the British decision. Germany called top diplomats from the EU’s six founding nations to a meeting Saturday, and the president of the European Council, Donald Tusk, said the bloc will meet without Britain at a summit next week to assess its future. Tusk vowed not to let the vote derail the European project.

“What doesn’t kill you, makes you stronger,” he said.

But already, far-right leaders in France and the Netherlands were calling for a similar anti-EU vote.

The referendum showed Britain to be a sharply divided nation: Strong pro-EU votes in the economic and cultural powerhouse of London and semi-autonomous Scotland were countered by sweeping anti-Establishment sentiment for an exit across the rest of England, from southern seaside towns to rust-belt former industrial powerhouses in the north.

“It’s a vindication of 1,000 years of British democracy,” commuter Jonathan Campbell James declared at the train station in Richmond, southwest London. “From Magna Carta all the way through to now we’ve had a slow evolution of democracy, and this vote has vindicated the maturity and depth of the democracy in our country.”

Others expressed anger and frustration. Olivia Sangster-Bullers, 24, called the result “absolutely disgusting.”

“Good luck to all of us, I say, especially those trying to build a future with our children,” she said.

Cameron called the referendum largely to silence voices to his right, then staked his reputation on keeping Britain in the EU. Former London Mayor Boris Johnson, who is from the same party, was the most prominent supporter of the “leave” campaign and now becomes a leading contender to replace Cameron.

The result also triggered turmoil in the left-of-center opposition Labour Party. Thousands of the party’s traditional working-class supporters defied the party’s call to vote “remain,” helping hand victory to campaign for a British exit, or Brexit.

Two Labour lawmakers made a move to topple leader Jeremy Corbyn, a staunch socialist whom they accused of lending lukewarm support to the pro-EU cause. Their motion of no-confidence in Corbyn will be discussed by Labour lawmakers next week, and could lead to a vote on his leadership.

The vote constituted a rebellion against the political, economic and social Establishment. All manner of groups — CEOs, scientists, soldiers — had written open letters warning of the consequences of an exit. Farage called the result “a victory for ordinary people against the big banks, big business and big politics.”

Donald Trump praised the decision during a visit to one of his golf courses in Scotland, saying Britons “took back their country. It’s a great thing.” He likened the vote to the U.S. sentiment that has propelled him to the presumptive Republican presidential nominee, saying people in the United States and the United Kingdom are angry about similar things.

“People are angry all over the world,” he said.

American President Barack Obama, who had urged Britain to stay, said the special relationship between the United States and the United Kingdom would endure the messy divorce from Europe that lies ahead.

After winning a majority in Parliament in the last election, Cameron negotiated a package of reforms that he said would protect Britain’s sovereignty and prevent EU migrants from moving to the U.K. to claim generous public benefits.

Critics charged that those reforms were hollow, leaving Britain at the mercy of bureaucrats in Brussels and doing nothing to stem the tide of European immigrants who have come to the U.K. since the EU expanded eastward in 2004. The “leave” campaign accuses the immigrants of taxing Britain’s housing market, public services and employment rolls.

Those concerns were magnified by the refugee crisis of the past year that saw more than 1 million people from the Middle East and Africa flood into the EU as the continent’s leaders struggled to come up with a unified response.

Cameron’s efforts to find a slogan to counter the “leave” campaign’s emotive “take back control” settled on “Brits don’t quit.” But the appeal to a Churchillian bulldog spirit and stoicism proved too little, too late.

The slaying of pro-Europe lawmaker Jo Cox a week before the vote brought a shocked pause to both campaigns and appeared to shift momentum away from the “leave” camp. While it isn’t clear whether her killer was influenced by the EU debate, her death aroused fears that the referendum had stirred demons it would be difficult to subdue.

The result triggers a new series of negotiations that is expected to last two years or more as Britain and the EU search for a way to separate economies that have become intertwined since the U.K. joined the bloc on Jan. 1, 1973. Until those talks are completed, Britain will remain a member of the EU.

Exiting the EU involves taking the unprecedented step of invoking Article 50 of the EU’s governing treaty. While Greenland left an earlier, more limited version of the bloc in 1985, no country has ever invoked Article 50, so there is no roadmap for how the process will work.

Authorities ranging from the International Monetary Fund to the U.S. Federal Reserve and the Bank of England have warned that a British exit will reverberate through a world economy that is only slowly recovering from the global economic crisis. The European Union is the world’s biggest economy and the U.K.’s most important trading partner, accounting for 45 percent of exports and 53 percent of imports.

In addition, the complex nature of Britain’s integration with the EU means that breaking up will be hard to do. The negotiations will go far beyond tariffs, including issues such as cross-border security, foreign policy cooperation and a common fisheries policy.

It will also affect the ability of professionals such as investment managers, accountants and lawyers to work in the EU, threatening London’s position as one of the world’s pre-eminent financial centers. The U.K. hosts more headquarters of non-EU firms than Germany, France, Switzerland and the Netherlands put together.

“We believe this outcome has serious implications for the City and many of our clients’ businesses with exposure to the U.K. and the EU,” said Malcolm Sweeting, senior partner of law firm Clifford Chance. “We are working alongside our clients to help them as they anticipate, plan for and manage the challenges the coming political and trade negotiations will bring.”

Associated Press